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Russell Hoult (shoulder), Richard Butcher (foot) and Adam Tann (knee) are all being nursed on the treatment table.
In addition to the trio, cameo substitute, Spencer Weir-Daley (ankle) and Charlton Athletic youngster, Nathaniel Wedderburn (knee) are both doubtful.
Jamie Forrester will serve the second part of his three-match ban, meaning that Sean Canham and Delroy Facey will lead the line once again.
After picking up his fifth yellow card of the season, Michael Johnson is set to serve a one game suspension, but this will begin after the Mariners' clash.
Therefore, John Thompson - who is set to stay with the club until the end of the season - can expect to operate in the centre of midfield.
Derby
Mike Newell is expected to name the same side that drew 2-2 with
The Mariners have no fresh worries but will be without winger, Peter Till and defender, Tom Newey, who both have hamstring troubles.