Scunthorpe United are expected to field a changed side from the one that trounced Stockport County 3-0 at the weekend.
Ex-Magpies' loanee, Krystian Pearce may feature following the extension of his loan from Birmingham City.
The young defender's spell with the Iron was lengthened because of injuries to fellow defenders, Andy Crosby, Joe Wilcox and Kenny Milne, who are all missing with knee injuries.
Also joining them is Izzy Iriekpen, who is not expected to return until the Brighton game because of a groin injury.
Martyn Woolford and Ian Morris are both hoping to start for the home side.
Notts County might hand a first start to summer recruit, Sean Canham,
who has yet to feature heavily in the black and white stripes.
This low priority fixture will be a fantastic opportunity to give the ex-Team Bath striker a run out - alongside the other fringe players - to show what he can do.
Just like in the Carling Cup clashes, Ian McParland is expected to name the likes of Neil Mackenzie, Ben Fairclough, Adam Tann and Spencer Weir-Daley.
Key figures, such as Michael Johnson, Myles Weston, Jamie Forrester and Matthew Hamshaw may drop to the bench.
Russell Hoult will also expect to start as he attempts to step up his fitness, as well as fight for the number one spot, currently occupied by Kevin Pilkington.
Adam Nowland and Gavin Strachan will both miss out with hamstring injuries, alongside Stephen Hunt, who is out with a long-term groin problem.